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Reduced serum content and increased matrix stiffness promote the cardiac myofibroblast transition in 3D collagen matrices.

INTRODUCTION: The fibroblast-myofibroblast transition is an important event in the development of cardiac fibrosis and scar formation initiated after myocardial ischemia. The goals of the present study were to better understand the contribution of environmental factors to this transition and determi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Galie, Peter A., Westfall, Margaret V., Stegemann, Jan P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110608/
https://ncbi.nlm.nih.gov/pubmed/21306921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2010.10.001
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