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Reduced serum content and increased matrix stiffness promote the cardiac myofibroblast transition in 3D collagen matrices.

INTRODUCTION: The fibroblast-myofibroblast transition is an important event in the development of cardiac fibrosis and scar formation initiated after myocardial ischemia. The goals of the present study were to better understand the contribution of environmental factors to this transition and determi...

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Detalhes bibliográficos
Main Authors: Galie, Peter A., Westfall, Margaret V., Stegemann, Jan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110608/
https://ncbi.nlm.nih.gov/pubmed/21306921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2010.10.001
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