Stiffness increases with myofibroblast content and collagen density in mesenchymal high grade serous ovarian cancer

Women diagnosed with high-grade serous ovarian cancers (HGSOC) are still likely to exhibit a bad prognosis, particularly when suffering from HGSOC of the Mesenchymal molecular subtype (50% cases). These tumors show a desmoplastic reaction with accumulation of extracellular matrix proteins and high c...

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Pubblicato in:Sci Rep
Autori principali: Mieulet, Virginie, Garnier, Camille, Kieffer, Yann, Guilbert, Thomas, Nemati, Fariba, Marangoni, Elisabetta, Renault, Gilles, Chamming’s, Foucauld, Vincent-Salomon, Anne, Mechta-Grigoriou, Fatima
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892556/
https://ncbi.nlm.nih.gov/pubmed/33603134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83685-0
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