The Over-expression of the β2 Catalytic Subunit of the Proteasome Decreases Homologous Recombination and Impairs DNA Double-Strand Break Repair in Human Cells

By a human cDNA library screening, we have previously identified two sequences coding two different catalytic subunits of the proteasome which increase homologous recombination (HR) when overexpressed in the yeast Saccharomyces cerevisiae. Here, we investigated the effect of proteasome on spontaneou...

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Detaylı Bibliyografya
Asıl Yazarlar: Collavoli, Anita, Comelli, Laura, Cervelli, Tiziana, Galli, Alvaro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110333/
https://ncbi.nlm.nih.gov/pubmed/21660142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/757960
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