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Mineral Composition is Altered by Osteoblast Expression of an Engineered G(s)-Coupled Receptor
Activation of the G(s) G protein–coupled receptor Rs1 in osteoblasts increases bone mineral density by 5- to 15-fold in mice and recapitulates histologic aspects of fibrous dysplasia of the bone. However, the effects of constitutive G(s) signaling on bone tissue quality are not known. The goal of th...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110278/ https://ncbi.nlm.nih.gov/pubmed/21526395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-011-9487-z |
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