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Conditional Expression of a Gi-Coupled Receptor in Osteoblasts Results in Trabecular Osteopenia

G protein-coupled receptors (GPCRs) coupled to activation of Gs, such as the PTH1 receptor (PTH1R), have long been known to regulate skeletal function and homeostasis. However, the role of GPCRs coupled to other G proteins such as Gi is not well established. We used the tet-off system to regulate th...

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Detalhes bibliográficos
Main Authors: Peng, J., Bencsik, M., Louie, A., Lu, W., Millard, S., Nguyen, P., Burghardt, A., Majumdar, S., Wronski, T. J., Halloran, B., Conklin, B. R., Nissenson, R. A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275363/
https://ncbi.nlm.nih.gov/pubmed/18048501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-0235
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