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Ligand-Mediated Activation of an Engineered G(s) G Protein-Coupled Receptor in Osteoblasts Increases Trabecular Bone Formation

Age-dependent changes in skeletal growth play important roles in regulating skeletal expansion and in the course of many diseases affecting bone. How G protein-coupled receptor (GPCR) signaling affects these changes is poorly understood. Previously, we described a mouse model expressing Rs1, an engi...

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Detalhes bibliográficos
Main Authors: Hsiao, Edward C., Millard, Susan M., Louie, Alyssa, Huang, Yong, Conklin, Bruce R., Nissenson, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840804/
https://ncbi.nlm.nih.gov/pubmed/20150184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0424
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