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The Fas-Associated Death Domain Protein (FADD) is Required in Apoptosis and TLR-induced Proliferative Responses in B Cells

The Fas-associated death domain protein FADD/Mort1 is a signaling adaptor protein which mediates the activation of caspase 8 during death receptor-induced apoptosis. Disruption of FADD in germ cells results in death receptor-independent embryonic lethality in mice. Previous studies indicated that in...

詳細記述

保存先:
書誌詳細
主要な著者: Imtiyaz, Hongxia Z., Rosenberg, Stephen, Zhang, Yuhang, Rahman, Ziaur S. M., Hou, Ying-Ju, Manser, Tim L., Zhang, Jianke
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110081/
https://ncbi.nlm.nih.gov/pubmed/16709845
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