The Fas-Associated Death Domain Protein (FADD) is Required in Apoptosis and TLR-induced Proliferative Responses in B Cells

The Fas-associated death domain protein FADD/Mort1 is a signaling adaptor protein which mediates the activation of caspase 8 during death receptor-induced apoptosis. Disruption of FADD in germ cells results in death receptor-independent embryonic lethality in mice. Previous studies indicated that in...

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Main Authors: Imtiyaz, Hongxia Z., Rosenberg, Stephen, Zhang, Yuhang, Rahman, Ziaur S. M., Hou, Ying-Ju, Manser, Tim L., Zhang, Jianke
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110081/
https://ncbi.nlm.nih.gov/pubmed/16709845
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