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Conditional FADD:GFP Knockout Mice Reveal FADD is Dispensable in Thymic Development but Essential in Peripheral T Cell Homeostasis
FADD/Mort1 is required for signaling induced by death-receptors such as Fas. In earlier studies, FADD-deficient mice died in utero and a FADD deficiency in embryonic stem cells inhibited T cell production in viable FADD(-/-)→RAG-1(-/-) chimeras. To analyze the temporal requirement of FADD in the dev...
Bewaard in:
| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2005
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110086/ https://ncbi.nlm.nih.gov/pubmed/16116191 |
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