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FADD deficiency impairs early hematopoiesis in the bone marrow
Signal transduction mediated by FADD represents a paradigm of co-regulation of apoptosis and cellular proliferation. During apoptotic signaling induced by death receptors including Fas, FADD is required for the recruitment and activation of caspase 8. In addition, a death receptor-independent functi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119601/ https://ncbi.nlm.nih.gov/pubmed/21115735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000648 |
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