NGF and proNGF Regulate Functionally Distinct mRNAs in PC12 Cells: An Early Gene Expression Profiling

The biological activities of NGF and of its precursor proNGF are quite distinct, due to different receptor binding profiles, but little is known about how proNGF regulates gene expression. Whether proNGF is a purely pro-apoptotic molecule and/or simply a “less potent NGF” is still a matter of debate...

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Detaylı Bibliyografya
Asıl Yazarlar: D'Onofrio, Mara, Paoletti, Francesca, Arisi, Ivan, Brandi, Rossella, Malerba, Francesca, Fasulo, Luisa, Cattaneo, Antonino
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109000/
https://ncbi.nlm.nih.gov/pubmed/21677785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020839
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