ProNGF Drives Localized and Cell Selective Parvalbumin Interneuron and Perineuronal Net Depletion in the Dentate Gyrus of Transgenic Mice

ProNGF, the precursor of mature Nerve Growth Factor (NGF), is the most abundant NGF form in the brain and increases markedly in the cortex in Alzheimer's Disease (AD), relative to mature NGF. A large body of evidence shows that the actions of ProNGF and mature NGF are often conflicting, dependi...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Fasulo, Luisa, Brandi, Rossella, Arisi, Ivan, La Regina, Federico, Berretta, Nicola, Capsoni, Simona, D'Onofrio, Mara, Cattaneo, Antonino
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299926/
https://ncbi.nlm.nih.gov/pubmed/28232789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00020
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