ProNGF Drives Localized and Cell Selective Parvalbumin Interneuron and Perineuronal Net Depletion in the Dentate Gyrus of Transgenic Mice

ProNGF, the precursor of mature Nerve Growth Factor (NGF), is the most abundant NGF form in the brain and increases markedly in the cortex in Alzheimer's Disease (AD), relative to mature NGF. A large body of evidence shows that the actions of ProNGF and mature NGF are often conflicting, dependi...

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Publicat a:Front Mol Neurosci
Autors principals: Fasulo, Luisa, Brandi, Rossella, Arisi, Ivan, La Regina, Federico, Berretta, Nicola, Capsoni, Simona, D'Onofrio, Mara, Cattaneo, Antonino
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299926/
https://ncbi.nlm.nih.gov/pubmed/28232789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00020
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