The Pharmacology of TD-8954, a Potent and Selective 5-HT(4) Receptor Agonist with Gastrointestinal Prokinetic Properties

This study evaluated the in vitro and in vivo pharmacological properties of TD-8954, a potent and selective 5-HT(4) receptor agonist. TD-8954 had high affinity (pK(i) = 9.4) for human recombinant 5-HT(4(c)) (h5-HT(4(c))) receptors, and selectivity (>2,000-fold) over all other 5-hydroxytryptamine...

詳細記述

保存先:
書誌詳細
主要な著者: Beattie, David T., Armstrong, Scott R., Vickery, Ross G., Tsuruda, Pamela R., Campbell, Christina B., Richardson, Carrie, McCullough, Julia L., Daniels, Oranee, Kersey, Kathryn, Li, Yu-Ping, Kim, Karl H. S.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Research Foundation 2011
主題:
Pharmacology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108484/
https://ncbi.nlm.nih.gov/pubmed/21687517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2011.00025
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料