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BRAF mutations in cutaneous melanoma are independently associated with age, anatomic site of the primary tumor and the degree of solar elastosis at the primary tumor site

Oncogenic BRAF mutations are more frequent in cutaneous melanoma from sites with little or moderate sun-induced damage than from sites with severe cumulative solar ultraviolet (UV) damage. We studied cutaneous melanomas from geographic regions with different levels of ambient UV radiation to delinea...

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Detalhes bibliográficos
Main Authors: Bauer, Jürgen, Büttner, Petra, Murali, Rajmohan, Okamoto, Ichiro, Kolaitis, Nicholas A, Landi, Maria Teresa, Scolyer, Richard A., Bastian, Boris C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107974/
https://ncbi.nlm.nih.gov/pubmed/21324100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2011.00837.x
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