BRAF mutations in cutaneous melanoma are independently associated with age, anatomic site of the primary tumor and the degree of solar elastosis at the primary tumor site

Oncogenic BRAF mutations are more frequent in cutaneous melanoma from sites with little or moderate sun-induced damage than from sites with severe cumulative solar ultraviolet (UV) damage. We studied cutaneous melanomas from geographic regions with different levels of ambient UV radiation to delinea...

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Autores principales: Bauer, Jürgen, Büttner, Petra, Murali, Rajmohan, Okamoto, Ichiro, Kolaitis, Nicholas A, Landi, Maria Teresa, Scolyer, Richard A., Bastian, Boris C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107974/
https://ncbi.nlm.nih.gov/pubmed/21324100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2011.00837.x
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