Survival According to BRAF-V600 Tumor Mutations – An Analysis of 437 Patients with Primary Melanoma

The prognostic impact of BRAF-V600 tumor mutations in stage I/II melanoma patients has not yet been analyzed in detail. We investigated primary tumors of 437 patients diagnosed between 1989 and 2006 by Sanger sequencing. Mutations were detected in 38.7% of patients and were associated with age, hist...

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Detalhes bibliográficos
Main Authors: Meckbach, Diana, Bauer, Jürgen, Pflugfelder, Annette, Meier, Friedegund, Busch, Christian, Eigentler, Thomas K., Capper, David, von Deimling, Andreas, Mittelbronn, Michel, Perner, Sven, Ikenberg, Kristian, Hantschke, Markus, Büttner, Petra, Garbe, Claus, Weide, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901680/
https://ncbi.nlm.nih.gov/pubmed/24475086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086194
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