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Enantioselective Organocatalytic α-Fluorination of Cyclic Ketones
The first highly enantioselective α-fluorination of ketones using organocatalysis has been accomplished. The long-standing problem of enantioselective ketone α-fluorination via enamine activation has been overcome via high-throughput evaluation of a new library of amine catalysts. The optimal system...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107934/ https://ncbi.nlm.nih.gov/pubmed/21247133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja111163u |
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