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Design and Characterization of Epitope-Scaffold Immunogens that Present the Motavizumab Epitope from Respiratory Syncytial Virus

Respiratory syncytial virus (RSV) is a major cause of respiratory tract infections in infants, but an effective vaccine has not yet been developed. An ideal vaccine would elicit protective antibodies while avoiding virus-specific T-cell responses, which have been implicated in vaccine-enhanced disea...

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Bibliographic Details
Main Authors: McLellan, Jason S., Correia, Bruno E., Chen, Man, Yang, Yongping, Graham, Barney S., Schief, William R., Kwong, Peter D.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107930/
https://ncbi.nlm.nih.gov/pubmed/21549714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.04.044
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