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Normal Atmospheric Oxygen Tension and the Use of Antioxidants Improve Hepatocyte Spheroid Viability and Function
BACKGROUND: Hepatocyte spheroids have been proposed for drug metabolism studies and in bioartificial liver devices. However, the optimal conditions required to meet the aerobic demands of mitochondria-rich hepatocyte spheroids is not well studied. We hypothesized that an optimal concentration of oxy...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107922/ https://ncbi.nlm.nih.gov/pubmed/21302300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22651 |
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