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Overall Survival As the Outcome for Randomized Clinical Trials With Effective Subsequent Therapies

We review how overall survival (OS) comparisons should be interpreted with increasing availability of effective therapies that can be given subsequently to the treatment assigned in a randomized clinical trial (RCT). We examine in detail how effective subsequent therapies influence OS comparisons un...

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Détails bibliographiques
Auteurs principaux: Korn, Edward L., Freidlin, Boris, Abrams, Jeffrey S.
Format: Artigo
Langue:Inglês
Publié: American Society of Clinical Oncology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107757/
https://ncbi.nlm.nih.gov/pubmed/21555691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.34.6056
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