Evaluation of the novel mitotic modulator ON 01910.Na in pancreatic cancer and preclinical development of an ex vivo predictive assay

Lignende værker

• Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate ON 01910.Na, a mitotic progression modulator, in human plasma
  af: Li, Jing, et al.
  Udgivet: (2007)
• Phase I Study of ON 01910.Na, a Novel Modulator of the Polo-Like Kinase 1 Pathway, in Adult Patients With Solid Tumors
  af: Jimeno, Antonio, et al.
  Udgivet: (2008)
• Discovery of a Clinical Stage Multi Kinase Inhibitor Sodium (E)-2-{2-Methoxy-5-[(2′, 4′, 6′-trimethoxystyrylsulfonyl)methyl]phenylamino}acetate (ON 01910.Na): Synthesis, Structure Activity Relationship and Biological Activity
  af: Reddy, M.V. Ramana, et al.
  Udgivet: (2011)
• Hydrothiolation of benzyl mercaptan to arylacetylene: application to the synthesis of (E) and (Z)-isomers of ON 01910·Na (Rigosertib(®)), a phase III clinical stage anti-cancer agent()
  af: Pallela, Venkat R., et al.
  Udgivet: (2013)
• Integrated preclinical and clinical development of S-trans, trans-farnesylthiosalicylic acid (FTS, Salirasib) in pancreatic cancer
  af: Laheru, Daniel, et al.
  Udgivet: (2012)