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From a Global View to Focused Examination: Understanding Cellular Function of Lipid Kinase VPS34-Beclin 1 Complex in Autophagy

Phosphoinositide 3 kinase Class III (PIK3C3) or VPS34-Beclin 1 complex plays a key role in the autophagy–lysosome pathway. Previous identification of numerous binding partners for VPS34-Beclin 1 suggested a complex scheme of the autophagy control mechanism. Recent large-scale screening of autophagy...

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Detalhes bibliográficos
Main Authors: Yue, Zhenyu, Zhong, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107464/
https://ncbi.nlm.nih.gov/pubmed/20846953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjq028
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