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From a Global View to Focused Examination: Understanding Cellular Function of Lipid Kinase VPS34-Beclin 1 Complex in Autophagy
Phosphoinositide 3 kinase Class III (PIK3C3) or VPS34-Beclin 1 complex plays a key role in the autophagy–lysosome pathway. Previous identification of numerous binding partners for VPS34-Beclin 1 suggested a complex scheme of the autophagy control mechanism. Recent large-scale screening of autophagy...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107464/ https://ncbi.nlm.nih.gov/pubmed/20846953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjq028 |
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