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Ligation of CD46 to CD40 inhibits CD40 signaling in B cells
CD40 induces B cells to switch to IgE in the presence of IL-4 and up-regulates their expression of the low-affinity receptor for IgE, CD23, which promotes the immune response to allergen complexed with IgE antibody. CD40 binds to CD40L and to the C4b-binding protein (C4BP) using distinct sites. CD46...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107443/ https://ncbi.nlm.nih.gov/pubmed/21393637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxq474 |
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