Role of low-frequency HIV-1 variants in failure of nevirapine-containing antiviral therapy in women previously exposed to single-dose nevirapine

In the OCTANE/A5208 study of initial antiretroviral therapy (ART) in women exposed to single-dose nevirapine (sdNVP) ≥6 mo earlier, the primary endpoint (virological failure or death) was significantly more frequent in the NVP-containing treatment arm than in the lopinavir/ritonavir-containing treat...

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Hlavní autoři: Boltz, Valerie F., Zheng, Yu, Lockman, Shahin, Hong, Feiyu, Halvas, Elias K., McIntyre, James, Currier, Judith S., Chibowa, Margret C., Kanyama, Cecelia, Nair, Apsara, Owino-Ong'or, Willis, Hughes, Michael, Coffin, John M., Mellors, John W.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107269/
https://ncbi.nlm.nih.gov/pubmed/21576473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105688108
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