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Short-course Combivir after Single Dose Nevirapine Reduces But Does Not Eliminate the Emergence of Nevirapine-Resistance in Women

BACKGROUND: In TOPS trial, 4 or 7 days of Combivir (CBV; zidovudine/lamivudine) with maternal single dose nevirapine (sdNVP) significantly reduced the emergence of NVP resistance as determined by virus population genotype. To detect NVP resistance with greater sensitivity, we analyzed TOPS samples b...

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Bibliografiska uppgifter
I publikationen:Antivir Ther
Huvudupphovsmän: Palmer, Sarah, Boltz, Valerie F., Chow, Jeremy Y., Martinson, Neil A., McIntyre, James A., Gray, Glenda E., Hopley, Mark J., Mayers, Douglas, Robinson, Patrick, Hall, David B., Maldarelli, Frank, Coffin, John M., Mellors, John W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6752704/
https://ncbi.nlm.nih.gov/pubmed/22293443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP1946
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