Optimization of allele-specific PCR using patient specific HIV consensus sequences for primer design

Allele-specific PCR based on subtype consensus sequences is a powerful technique for detecting low frequency drug resistant mutants in HIV-1 infected patients. However, this approach can be limited by genetic variation in the region complementary to the primers, leading to variability in allele dete...

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Vydáno v:J Virol Methods
Hlavní autoři: Boltz, Valerie F., Maldarelli, Frank, Martinson, Neil, Morris, Lynn, McIntyre, James A., Gray, Glenda, Hopley, Mark J., Kimura, Toshio, Mayers, Douglas L., Robinson, Patrick, Mellors, John W., Coffin, John M., Palmer, Sarah E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734888/
https://ncbi.nlm.nih.gov/pubmed/19948190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2009.11.025
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