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Solution Structures of the Acyl Carrier Protein Domain from the Highly Reducing Type I Iterative Polyketide Synthase CalE8

Biosynthesis of the enediyne natural product calicheamicins γ(1) (I) in Micromonospora echinospora ssp. calichensis is initiated by the iterative polyketide synthase (PKS) CalE8. Recent studies showed that CalE8 produces highly conjugated polyenes as potential biosynthetic intermediates and thus bel...

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Detalhes bibliográficos
Main Authors: Lim, Jackwee, Kong, Rong, Murugan, Elavazhagan, Ho, Chun Loong, Liang, Zhao-Xun, Yang, Daiwen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107222/
https://ncbi.nlm.nih.gov/pubmed/21674045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020549
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