Rigidifying Acyl Carrier Protein Domain in Iterative Type I PKS CalE8 Does Not Affect Its Function

Acyl carrier protein (ACP) domains shuttle acyl intermediates among the catalytic domains of multidomain type I fatty acid synthase and polyketide synthase (PKS) systems. It is believed that the unique function of ACPs is associated with their dynamic property, but it remains to be fully elucidated...

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Detalhes bibliográficos
Main Authors: Lim, Jackwee, Sun, Huihua, Fan, Jing-Song, Hameed, Iman Fahim, Lescar, Julien, Liang, Zhao-Xun, Yang, Daiwen
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433619/
https://ncbi.nlm.nih.gov/pubmed/23009853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.08.006
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