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Production of Octaketide Polyenes by the Calicheamicin Polyketide Synthase CalE8: Implications for the Biosynthesis of Enediyne Core Structures

Enediyne antibiotics are categorized according to the presence of either a 9- or 10-membered ring within their polyketide-derived core structures. Recent literature reports have favored the notion that biosynthetic divergence of the two structural families is determined by the enediyne polyketide sy...

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Detalhes bibliográficos
Main Authors: Belecki, Katherine, Crawford, Jason M., Townsend, Craig A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760317/
https://ncbi.nlm.nih.gov/pubmed/19689130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja904391r
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