Nuclear Accumulation of Stress Response mRNAs Contributes to the Neurodegeneration Caused by Fragile X Premutation rCGG Repeats

Fragile X–associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder seen in Fragile X premutation carriers. Previous studies found that Fragile X rCGG repeats are sufficient to cause neurodegeneration and that the rCGG repeat-binding proteins Pur α and hnRNP A2/B1 can modulate rCGG–m...

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Detaylı Bibliyografya
Asıl Yazarlar: Qurashi, Abrar, Li, Wendi, Zhou, Jian-Ying, Peng, Junmin, Jin, Peng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107199/
https://ncbi.nlm.nih.gov/pubmed/21655086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002102
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