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Mutation of the His ligand in mitoNEET stabilizes the 2Fe–2S cluster despite conformational heterogeneity in the ligand environment

MitoNEET is the only identified Fe–S protein localized to the outer mitochondrial membrane and a 1.5 Å resolution X-ray analysis has revealed a unique structure [Paddock et al. (2007 ▶), Proc. Natl Acad. Sci. USA, 104, 14342–14347]. The 2Fe–2S cluster is bound with a 3Cys–1His coordination which def...

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Bibliografiset tiedot
Päätekijät: Conlan, Andrea R., Paddock, Mark L., Homer, Christina, Axelrod, Herbert L., Cohen, Aina E., Abresch, Edward C., Zuris, John A., Nechushtai, Rachel, Jennings, Patricia A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: International Union of Crystallography 2011
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107049/
https://ncbi.nlm.nih.gov/pubmed/21636891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444911011577
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