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Enantioselective Dichlorination of Allylic Alcohols

The development of an enantioselective allylic alcohol dichlorination catalyzed by dimeric cinchona alkaloid derivatives and employing aryl iododichlorides as chlorine sources is reported. Reaction optimization, exploration of the substrate scope, and a model for stereoinduction are presented.

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Bibliografske podrobnosti
Main Authors: Nicolaou, K. C., Simmons, Nicholas L., Ying, Yongcheng, Heretsch, Philipp M., Chen, Jason S.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107004/
https://ncbi.nlm.nih.gov/pubmed/21542622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja202555m
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