Fidelity and Mutational Spectrum of Pfu DNA Polymerase on a Human Mitochondrial DNA Sequence
The study of rare genetic changes in human tissues requires specialized techniques. Point mutations at fractions at or below 10(−6) must be observed to discover even the most prominent features of the point mutational spectrum. PCR permits the increase in number of mutant copies but does so at the e...
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| Gepubliceerd in: | Genome Res |
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| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
1997
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9267808/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.7.8.843 |
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