Fidelity and Mutational Spectrum of Pfu DNA Polymerase on a Human Mitochondrial DNA Sequence
The study of rare genetic changes in human tissues requires specialized techniques. Point mutations at fractions at or below 10(−6) must be observed to discover even the most prominent features of the point mutational spectrum. PCR permits the increase in number of mutant copies but does so at the e...
Gardado en:
| Publicado en: | Genome Res |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
1997
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9267808/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.7.8.843 |
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