Caveolin-1–eNOS signaling promotes p190RhoGAP-A nitration and endothelial permeability

Endothelial barrier function is regulated by adherens junctions (AJs) and caveolae-mediated transcellular pathways. The opening of AJs that is observed in caveolin-1(−/−) (Cav-1(−/−)) endothelium suggests that Cav-1 is necessary for AJ assembly or maintenance. Here, using endothelial cells isolated...

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Autors principals: Siddiqui, M. Rizwan, Komarova, Yulia A., Vogel, Stephen M., Gao, Xiaopei, Bonini, Marcelo G., Rajasingh, Johnson, Zhao, You-Yang, Brovkovych, Viktor, Malik, Asrar B.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105546/
https://ncbi.nlm.nih.gov/pubmed/21624953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201012129
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