PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

Atherosclerosis is readily observed in regions of blood vessels where disturbed blood flow (d-flow) is known to occur. A positive correlation between protein kinase C ζ (PKCζ) activation and d-flow has been reported, but the exact role of d-flow–mediated PKCζ activation in atherosclerosis remains un...

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Bibliographic Details
Main Authors: Heo, Kyung-Sun, Lee, Hakjoo, Nigro, Patrizia, Thomas, Tamlyn, Le, Nhat-Tu, Chang, Eugene, McClain, Carolyn, Reinhart-King, Cynthia A., King, Michael R., Berk, Bradford C., Fujiwara, Keigi, Woo, Chang-Hoon, Abe, Jun-ichi
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2011
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105539/
https://ncbi.nlm.nih.gov/pubmed/21624955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010051
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