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p62 Binding to Protein Kinase C ζ Regulates Tumor Necrosis Factor α–Induced Apoptotic Pathway in Endothelial Cells

OBJECTIVE: Protein kinase C (PKC) ζ is a key pathological mediator of endothelial cell apoptosis. p62 is a scaffold protein that regulates several cell signaling pathways by binding to target proteins. Because PKCζ and p62 contain Phox/Bem1p (PB1) modules that mediate protein–protein interactions, w...

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Bibliografiska uppgifter
Huvudupphovsmän: Kim, Geun-Young, Nigro, Patrizia, Fujiwara, Keigi, Abe, Jun-ichi, Berk, Bradford C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084716/
https://ncbi.nlm.nih.gov/pubmed/23023376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300054
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