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Biophysical analysis and small-angle X-ray scattering-derived structures of MeCP2–nucleosome complexes

MeCP2 is a highly abundant chromatin architectural protein with key roles in post-natal brain development in humans. Mutations in MeCP2 are associated with Rett syndrome, the main cause of mental retardation in girls. Structural information on the intrinsically disordered MeCP2 protein is restricted...

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Detalhes bibliográficos
Main Authors: Yang, Chenghua, van der Woerd, Mark J., Muthurajan, Uma M., Hansen, Jeffrey C., Luger, Karolin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105411/
https://ncbi.nlm.nih.gov/pubmed/21278419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr005
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