Enhancement of the cleavage rates of DNA-armed hammerhead ribozymes by various divalent metal ions.
In order to characterize structure-function relationships, the kinetic behavior of chimeric RNA/DNA ribozyme was compared with that of all RNA ribozyme. Determined kcat values were proven to represent the chemical-cleavage step and not the product-dissociation step. In agreement with the finding by...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1993
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310531/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7506830/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.24.5656 |
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