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Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain

The conventional design of high affinity drugs targeted to a single molecule has not resulted in clinically useful therapies for pain relief. Recent reviews have suggested that newly designed analgesic drugs should incorporate multiple targets. The distributions of cholecystokinin (CCK) and CCK rece...

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Bibliografske podrobnosti
Main Authors: Hanlon, Katherine E., Herman, Dave S., Agnes, Richard S., Largent-Milnes, Tally M., Kumarasinghe, Isuru R., Ma, Sho W., Guo, Wenhong, Lee, Yeon-Sun, Ossipov, Michael H., Hruby, Victor J., Lai, Josephine, Porreca, Frank, Vanderah, Todd W.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105124/
https://ncbi.nlm.nih.gov/pubmed/21550594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2011.04.024
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