Oxycodone Plus Ultra-Low-Dose Naltrexone Attenuates Neuropathic Pain and Associated μ-Opioid Receptor–G(s) Coupling

Both peripheral nerve injury and chronic opioid treatment can result in hyperalgesia associated with enhanced excitatory neurotransmission at the level of the spinal cord. Chronic opioid administration leads to a shift in μ-opioid receptor (MOR)–G protein coupling from G(i/o) to G(s) that can be pre...

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Detaylı Bibliyografya
Yayımlandı:J Pain
Asıl Yazarlar: Largent-Milnes, Tally M., Guo, Wenhong, Wang, Hoau-Yan, Burns, Lindsay H., Vanderah, Todd W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469510/
https://ncbi.nlm.nih.gov/pubmed/18468954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2008.03.005
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