Variable HIV peptide stability in human cytosol is critical to epitope presentation and immune escape

Induction of virus-specific CD8(+) T cell responses is critical for the success of vaccines against chronic viral infections. Despite the large number of potential MHC-I–restricted epitopes located in viral proteins, MHC-I–restricted epitope generation is inefficient, and factors defining the produc...

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Hauptverfasser: Lazaro, Estibaliz, Kadie, Carl, Stamegna, Pamela, Zhang, Shao Chong, Gourdain, Pauline, Lai, Nicole Y., Zhang, Mei, Martinez, Sergio A., Heckerman, David, Le Gall, Sylvie
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104749/
https://ncbi.nlm.nih.gov/pubmed/21555856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44932
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