Modulation of oligonucleotide duplex and triplex stability via hydrophobic interactions.
Synthetic oligonucleotides have been proposed as a new rationally designed class of pharmaceuticals with a mechanism of action based upon a Watson-Crick and/or Hoogsteen type of base pairing with RNA or DNA regions of interest. Two series of 3'-cholesterol and/or 5'-cholesterol conjugated oligonucle...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1993
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310473/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8290352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.25.5909 |
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