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Modulation of oligonucleotide duplex and triplex stability via hydrophobic interactions.
Synthetic oligonucleotides have been proposed as a new rationally designed class of pharmaceuticals with a mechanism of action based upon a Watson-Crick and/or Hoogsteen type of base pairing with RNA or DNA regions of interest. Two series of 3'-cholesterol and/or 5'-cholesterol conjugated...
Uloženo v:
| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1993
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC310473/ https://ncbi.nlm.nih.gov/pubmed/8290352 |
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