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Modulation of oligonucleotide duplex and triplex stability via hydrophobic interactions.

Synthetic oligonucleotides have been proposed as a new rationally designed class of pharmaceuticals with a mechanism of action based upon a Watson-Crick and/or Hoogsteen type of base pairing with RNA or DNA regions of interest. Two series of 3'-cholesterol and/or 5'-cholesterol conjugated...

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Bibliografische gegevens
Hoofdauteurs: Gryaznov, S M, Lloyd, D H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1993
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC310473/
https://ncbi.nlm.nih.gov/pubmed/8290352
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