Stabilisation of TG- and AG-containing antiparallel DNA triplexes by triplex-binding ligands

We have used DNase I footprinting to examine the interaction of several triplex-binding ligands with antiparallel TG- and AG-containing triplexes. We find that although a 17mer TG-containing oligonucleotide on its own fails to produce a footprint at concentrations as high as 30 µM, this interaction...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Keppler, Melanie D., Neidle, Stephen, Fox, Keith R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11328877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.9.1935
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