Carregant...
Differences in the accessibility of methylated and unmethylated DNA to DNase I.
DNase I binds in the minor groove of DNA and is used as an enzymatic tool to investigate the interaction of proteins with DNA. Here we show that the major groove located 5-methyldeoxycytidine can enhance or inhibit the cleavage rates of DNA by DNase I. This effect may be caused in part by changes in...
Guardat en:
| Autors principals: | , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1993
|
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC310463/ https://ncbi.nlm.nih.gov/pubmed/8290342 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|