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Detection of point mutations in human DNA by analysis of RNA conformation polymorphism(s).
RNA molecules were found to separate into numerous metastable conformational forms upon non-denaturing gel electrophoresis. The equilibration of the conformations was accelerated by heating or mild denaturing conditions. Single-base substitutions in the sequence of the RNAs caused changes in the con...
Uloženo v:
| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1992
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC310425/ https://ncbi.nlm.nih.gov/pubmed/1371351 |
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