Multipyrene Tandem Probes for Point Mutations Detection in DNA

Here we report design, synthesis and characterization of highly sensitive, specific and stable in biological systems fluorescent probes for point mutation detection in DNA. The tandems of 3′- and 5′-mono- and bis-pyrene conjugated oligo(2′-O-methylribonucleotides), protected by 3′-“inverted” thymidi...

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Hauptverfasser: Kholodar, Svetlana A., Novopashina, Darya S., Meschaninova, Mariya I., Venyaminova, Alya G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886547/
https://ncbi.nlm.nih.gov/pubmed/24455205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/860457
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